The College of Liberal Arts and Sciences has launched the Health Research Collaborative (HRC) to elevate the visibility, impact, and external funding of health-related research at CU Denver. In its inaugural year, the HRC will prioritize the Health Humanities, recognizing their critical role in shaping how health, illness, care, and equity are understood and addressed. This proposal seeks to accelerate health humanities research by supporting the development of Health Humanities Research Teams (HHRTs) that will generate 2–3 competitive grant applications (targeting NEH Collaborative Grants) and produce an edited health humanities volume, positioning the downtown campus as a national hub where health humanities scholarship thrives.
Phase 1 focused on establishing the HRC as an interdisciplinary infrastructure for collaboration and research development. Phase 2, launching in summer 2026, will involve a scoping analysis of the landscape of Health Humanities research to accelerate Health Humanities research. This data-driven scoping effort will strategically position HHRTs to pursue external funding aligned with their scholarly strengths and emerging opportunities. Throughout the year, our HHRTs will share and receive feedback on their work and meet with RDO staff to develop funding applications that synthesize our research areas.
At a time when healthcare systems face crises of trust, equity, and communication, technical solutions alone are insufficient. Health Humanities strengthen public trust, promote community engagement, and position our campus as a leader in the human dimensions of health. A modest investment in health humanities fosters strategic capacity poised for larger investments in future humanities initiatives.
This summer, we plan to film Miss Lonelyheart’s Memory Light, a feature film blending magical realism and coming-of-age drama set in 1990’s Denver. Florence Young will act as the writer/director, and Nathan Thompson will act as Production Designer. This activity will advance both of our creative practices while directly serving the university’s mission to ensure student career readiness.
The story follows 8-year-old Grace, a child with undiagnosed PTSD who runs away to confront her estranged, violent father and resolve the mystery of her mother’s death. She finds an unexpected mentor in Miss Lonelyheart, an elderly recluse whose handmade "memory light" acts as an emotional portal into the past.
Shot extensively on campus, the film will weave the Auraria displacement history into the atmosphere, rooting the story in CU Denver’s unique heritage. Though it is a deeply personal story, this project will also serve as a vocational engine for CU Denver students, placing them in key creative roles like Director of Photography, Art Director, Sound Designer and Editor to provide real-world mentorship and professional credits.
This project advances CAM’s mission by placing students in key creative roles to ensure career readiness through real-world engagement. It embodies CAM's values by supporting 'risktakers' through an honest, lyrical exploration of trauma. Finally, the project serves as a bridge to the broader film community through strategic festival participation and local industry engagement.
For decades, public administration scholars have considered social equity as a ‘pillar’ of the discipline. However, a lack of clarity around the definition, operationalization, and measure of equity, as well as a disconnect between theory and practice remain as important challenges for equity-centered scholarship. These shortcomings become even more relevant amidst the recent legal, cultural, and political backlash against diversity, equity and inclusion, (DEI) that may impact how public organizations approach their equity-oriented work at the local level. This research will explore these issues in the case of the Denver Mayor's Office of Social Equity and Innovation (OSEI). The questions that will guide this study are: How is OSEI understanding, operationalizing and trying to advance equity given the current legal, political and cultural context? What are some of the challenges that OSEI currently face to advance equity in the City and County of Denver? Which strategies seem to be working to advance equity at the local level in these turbulent times? To answer these questions, a qualitative case study will be employed to gain a deep understanding of the agency, its current challenges and possible successful strategies. Findings from this work will be the basis for a nationwide collaborative project that will pursue funds from the Russell Sage Foundation to study how Equity Offices across the U.S. can advance their missions at the local level in these turbulent times.
This proposal seeks support for a pilot study examining how PreK-2 teachers conceptualize and enact civic literacies with young children, particularly in relation to migration. When book bans have reached historic highs, divisive concepts legislation restricts equity-focused teaching in 22 states, and migration remains politically charged, teachers seek support to foster belonging but are constrained by limited resources. Early childhood civic education too often becomes reduced to superficial narratives that position immigrant children as passive recipients rather than rights-holders and civic actors.
In Fall 2025 and Spring 2026, we facilitated teacher inquiry groups exploring civic literacies and belonging. This dialogue revealed that early childhood educators face unique challenges and limited resources for teaching civic literacies beyond surface-level diversity celebration. This pilot systematically investigates these challenges through a qualitative survey (N=50), interviews (N=7), and picturebook content analysis (N=15-20), documenting teachers' practices, constraints, and needs.
This seed grant will produce three deliverables: 1) a scholarly manuscript synthesizing findings across grade levels; 2) a practitioner guide with annotated books and pedagogical strategies; and 3) an external grant proposal to the William T. Grant Foundation or Spencer Foundation. By systematically documenting challenges and needed resources, we translate theoretical proposals into evidence-based frameworks to reduce inequality and foster belonging and civic engagement. This addresses an urgent need: early childhood teachers require support to center children's civic participation at a time when such work faces unprecedented challenges.
Our innovative, theoretically-grounded, and multi-disciplinary study examines education disparities in psychological well-being (PWB), health, and mortality in two national longitudinal studies: the Health and Retirement Study (ages 50+) and the Midlife in the United States Study (ages 20-75 at baseline). PWB reflects the extent to which people feel happy and satisfied and see themselves as leading meaningful and fulfilling lives and is a central but understudied element of healthy aging. Maximizing wellness (and not merely reducing the share of the population in poor health) is directly aligned with national health priorities articulated in Healthy People 2030. PWB also holds promise for mitigating educational disparities in health and mortality that define the U.S. experience. Understanding changes in PWB throughout midlife and old age is especially important given recent evidence that shows declining levels of wellbeing in the U.S. population, while deaths of despair and loneliness are on the rise. The specific aims (1) use longitudinal data to identify trajectories in PWB across midlife and old age and the ages where education disparities in PWB are growing or closing over time, and (2) identify the ages where education disparities in PWB are most closely associated with incident hypertension, incident diabetes, and mortality. Our R01 proposal to NIH was reviewed on January 23, 2026, receiving an impact score of 36 (29th percentile). Seed funding from RDO will support additional preliminary work and revisions to the R01 proposal that we plan to resubmit for the February 2027 deadline.
Mutations in the mitochondrial intermembrane protein coiled-coil-helix-coiled-coil-helix domain-containing 10 (CHCHD10) are critically linked to the progression of neurodegenerative diseases such as Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). While CHCHD10 is known to be essential for maintaining mitochondrial cristae integrity and cellular respiration, the specific structural mechanisms by which its mutations disrupt metabolic pathways remain a significant knowledge gap. This project utilizes recombinant DNA and stable isotope labeling technologies to produce CHCHD10 and its pathogenic S59L mutant for high-resolution analysis.
Building on observations that the protein’s partially disordered nature hinders standard purification and stability, we are designing specialized constructs that isolate structured regions. This strategic approach streamlines the purification process and enables the use of Nuclear Magnetic Resonance (NMR) spectroscopy to obtain multidimensional structural fingerprints. Furthermore, we characterize the stability and molecular binding affinities of these constructs through Circular Dichroism (CD) and Isothermal Titration Calorimetry (ITC).
By defining how the interactions between secondary structures and protein dynamics influence overall stability, this research aims to illuminate the neurobiological pathways underlying ALS-FTD. Ultimately, this work aligns with CU Denver’s 2030 Strategic Plan Goal 3, propelling the university toward international recognition through impactful contributions to the field of molecular research.
Complex systems such as power grids, wireless networks, and transportation systems involve interactions that vary across different relationship types—requiring multigraphs (graphs with multiple types of edges) for accurate modeling. For example, in power systems, deploying sensors at every node is prohibitively expensive, making efficient signal sampling critical; yet current methods are incomplete and unreliable when applied to multigraph structures. Existing theoretical tools fail to account for simultaneous, non-commutative interactions across edge types, fundamentally limiting our ability to reconstruct information on these structures. This project addresses this gap by developing a rigorous theoretical framework and practical algorithms for optimal sampling on multigraphs.
The PI brings deep expertise in sampling theory, having developed blue-noise sampling strategies for graphs (IEEE TSIPN 2019), characterized optimal sampling sets in graph families (IEEE DSW 2019), and pioneered sampling theory for graphon signals with convergence guarantees (IEEE TSP 2025). Under the PI’s supervision, a graduate student will carry out computational experiments and algorithm implementation while the PI leads theoretical development using non-commutative algebraic structures. The theoretical results will directly contribute to reducing the number of sensors needed for accurate power grid state estimation—a critical bottleneck that forces utilities to rely on sparse, incomplete measurements. These advances will be validated through working software tools; the software serves as the primary vehicle for demonstrating the theoretical contributions, making the two inseparable.
This seed funding will generate proof-of-concept results and validated software necessary to launch a competitive NSF proposal to the EPCN or CPS programs, targeting submission in Fall 2026.
Hot springs, found in mountainous landscapes across the globe, are equal parts cultural and natural phenomenon. Today hot springs are often developed and designed as commercial spas and tourist resorts, although some remain as natural physical settings. Contemporary risks associated with hot springs sites span from geothermal energy plans, to declines of water within the system, to neglect and loss of historic structures and fragile natural settings.
Addressing these concerns, the grant will articulate a research agenda, and produce a detailed precis for two core Landscape Architecture classes (Fall 2026) that comprise a 9 credit immersive studio/seminar experience. Students will catalogue and document selected hot springs sites and assess their geologic and hydraulic properties; explore narratives and ideas attached to these cultural sites; and engage in a project that reimagines how people might sustainably access and utilize hot springs in Colorado. The class will connect with indigenous tribes to explore hot springs on their lands. Hot springs require thoughtful protections and sustainable designs that allow visitors access to these fragile, alluring sites.
The timeliness of this topic in light of climate change, loss of sites, and development pressures affects landscapes around the world affirms capacity for funding of future efforts. Grant products will include all work by the students and faculty; these will inform a body of additional engaged learning experiences, new research, and publications that will address the legacy and potential of Colorado’s hot springs, and direct thinking towards the future environmental and cultural value of hot springs globally.
CU Denver
Lawrence Street Center
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Denver, CO 80204
303-315-5826